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Zuma to test for HIV on World Aids Day

Trial SA vaccines bring new hope

Nov 30, 2009 10:55 PM | By Nkosana Lekotjolo

South Africa will mark World Aids Day with greater hope than ever before.


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quote Only minor adverse reactions to the vaccines in safety trials quote

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President Jacob Zuma will be tested for HIV, and his health minister, Aaron Motsoaledi, has committed himself to doing the same soon, breaking with the previous government's hands-off approach to the epidemic.

But there is also hope in the encouraging results of tests of two South African-developed HIV vaccines that scientists believe will soon save lives.

Though the SA Aids Vaccine Initiative's vaccines are at least a decade away from preventing infection, the latest developments are a huge leap forward.

The crucial first safety phase of the trials of the vaccines are nearly complete and the results are encouraging.

The 36 South Africans and 12 US citizens participating in the clinical tests have shown only minor reactions to the vaccines.

Elise Levendal, interim director of the SA Aids Vaccine Initiative, explained:

  • Phase 1, which is close to successful completion, primarily tests for safety, tolerability and side effects. If successful, it will be followed by trials involving more volunteers.
  • Phase 2 trials test for vaccine safety, immune response and the best way to administer the vaccines, by injection or orally. This phase could begin as early as July.
  • Phase 3 tests if the vaccine is effective, and whether it protects against infection or slows the progression to Aids.

Levendal said: "We have not heard of any severe symptoms from participants reacting to the vaccines. Only minor symptoms, such as headaches, reddish skin and a little swelling after the injection of the vaccines were seen, which is normal.

"The most important result we are hoping to get from phase 1 is to find out if the vaccines are safe and that the immune response of the participants is good."

Scientists have been working on the vaccines' development since 1999.

The clinical tests are conducted by the SA Medical Research Council in partnership with the Vaccine Trials Network and the US National Institutes of Health.

Prof Glenda Gray, the lead clinical investigator at Chris Hani-Baragwanath Hospital, in Soweto, said one of the clinical test results was "promising".

"Our products are really good and I'm very hopeful that they will be successful," she said.

Tsholofelo Mokata, 21, a participant in the vaccine trials, said: "I'm excited that I'm taking part in an experiment that, if it succeeds, will save a lot of lives. My view of HIV/Aids has changed. I now have one partner," said Mokata.

But the government and health department experts, hoping to halve new HIV/Aids infections by 2011 and ensure that 80% of people living with the virus receive antiretrovirals, said there is hard work ahead.

The health ministry told The Times yesterday that 5.4 million people in the country were HIV-positive.

Mark Heywood, chief executive of the SA National Aids Council, said that if the country were to reduce the number of Aids deaths, Zuma and Motsoaledi would have to lead from the front.

"Zuma and Motsoaledi will have to translate their objectives into tangible results.

"People need to internalise HIV and make it relevant to them," said Heywood.

Nokhwezi Hoboyi, of the Treatment Action Campaign, praised Motsoaledi, saying "the new minister is willing to listen to us".

But experts have warned that the country's slow response to Aids has triggered a time bomb that might leave one in three children orphaned.

Motsoaledi said the government's message for today was: "It is the responsibility of all to stop the spread of HIV/Aids."

  • Zuma will address the nation on SABC television and radio at noon
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Comments

Dec 1 2009 02:00:42 AM
Mole85
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Atleast he is seen as doing something instead of sitting back, writing memoirs, travelling the globe and prescribing beetroot...

Getting tested is the first step. Lets hope the population gets tested in the millions!!
Dec 1 2009 02:02:46 AM
Tackler
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Being tested in public but keeping the results private is one big fat cop-out. Sizzle with no steak. Transparency demands he reveals his test results.
Dec 1 2009 06:08:55 AM
DDarko
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We can only hope for the result that will be best for all the people of South Africa, Africa and the world.

Let us all think positive.
Dec 1 2009 06:24:54 AM
Vlad
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I agree @ Tackler... why all the hype, when we the SERVING public have the right to know if our Saviour is Negative.... or Positive..or just plain screwed???

....and yes.... We, the SA public, SERVE our masters in Govt, National, Provincial and Local... they seem to have gotten it mixed up along the way.... (sic)
Dec 1 2009 06:54:50 AM
pommie abroad
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He can't be positive, he had a shower - can he?
Dec 1 2009 06:58:48 AM
VinceRSA
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As a public figurehead this is a publicity stunt without a doubt BUT ONE THAT IS LONG OVERDUE!

Next, resolve to go to court and face those hundreds and hundreds of criminal (NOT Political) charges that were well investigated for years with "no bearing of political influence" and then we might even start to develop some respect!
Dec 1 2009 07:05:35 AM
ugen
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Now we will know if the shower really works
Dec 1 2009 07:14:23 AM
kingluu
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There is absolutely no need for that. i think after the whole shower thing and considering the number of women the man have, it is too late to try and lead the battle agaist HIV/ AIDS.
Dec 1 2009 07:27:53 AM
Sbonelo
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Will it make any difference whether he is positive or negative, he will still be the president of us ALL.
Dec 1 2009 07:35:47 AM
madlamini
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This is just a publicity stunt which the previous president also did(TM), what is the point of making a fuss about taking a test and not revealing the results, yes i know that it's a private issue and therefore he does not have to make his results public as the follower's of the messiah will soon point out but can he also keep it to himself that he is taking the test.



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