Bafana's winless streak has now stretched to eight games in a row after the goalless draw against Senegal at Moses Mabhida stadium on Wednesday night.
The Bafana coach admitted days before the match that he was under pressure.
He believes that getting a victory will not only release him from the clutches of depression, but will do the same for his children and Bafana players.
"It's become a test of character for me, my family, my kids and my players. We need a win to break the ice. My kids take stress and it's not easy on me as well."
Mosimane last jumped for joy in August, when Bafana beat Burkina Faso 3-0 at Ellis Park. However, after eight games without that feeling, the coach has run out of excuses but, he said, not ideas.
"What blame do I take for the kind of technique being used when chances have to be taken? The chance that May Mahlangu had early in [Wednesday night's] game, I thought, could have turned things around," he said.
"I also expected Teko Modise to take the chance (in the 90th minute) but the technique was wrong."
Mosimane was booed by the fans minutes before the game as his name was called out on the stadium speakers. The coach was jeered by fans again when he walked to the dressing room after the final whistle.
But he was surprisingly calm after the match.
"I've been a player before and have experienced these things. I know what my players are going through, but I have the strength to endure and persevere," he said.
"We will turn this around because I know what these players can offer. I think I still have age on my side to change things around and try new formations.
"Ethiopia won't stand [up to] the attacking style we showed against Senegal and I'm confident we will be top of the group by winning our first game," said Mosimane.
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