In contrast, Goerges is in the Wimbledon semi-finals for the first time.
The 29-year-old had suffered five successive opening round defeats at the All England Club before this year.
It also took her until her 42nd Grand Slam appearance to finally get through to the last four at a major.
Yet Goerges insists she can cause an massive upset against Williams.
"It is a great opportunity to play Serena here where she has won so many times and is a great champion. I think everyone here has a great chance so you have to take it," Goerges said.
Angelique Kerber, the German 11th seed, faces former French Open champion Jelena Ostapenko in the other semi-final.
Ostapenko struggled with the pressure of defending her maiden Grand Slam title, losing in the first round of the recent French Open.
But that lifted a weight off her shoulders at the All England Club, where she has become the first Latvian to make a Wimbledon semi-final.
The 21-year-old is the only female player yet to drop a set in this year's tournament.
"At the French Open a couple weeks ago I had so much pressure. It's now all gone," Ostapenko said.
"I'm just enjoying the moment. It's so much fun."
However, Kerber, beaten by Serena in the 2016 Wimbledon final, doesn't believe Ostapenko will be able to play completely free of anxiety with the title match within touching distance.
Kerber, the 2016 Australian and US Open champion, said: "I mean, the pressure is not always on my side. She (Ostapenko) won a Grand Slam, as well."