WATCH | Rats find it relaxing to take joyrides in tiny cars, say mental health researchers

24 October 2019 - 11:37 By AFP Relaxnews
Scientists have reported successfully training rodents to drive tiny cars and found that learning the task lowered their stress levels.
Scientists have reported successfully training rodents to drive tiny cars and found that learning the task lowered their stress levels.
Image: HO - University of Richmond/AFP

Sometimes life really can be a rat race.

US scientists have reported successfully training a group of the rodents to drive tiny cars in exchange for bits of Froot Loops cereal, and found that learning the task lowered their stress levels.

Their study not only demonstrates how sophisticated rat brains are, but could one day help in developing new non-pharmaceutical forms of treatment for mental illness, said senior study author Kelly Lambert of the University of Richmond.

Lambert said she had long been interested in neuroplasticity — how the brain changes in response to experience and challenges — and particularly wanted to explore how well rats that were housed in more natural settings ("enriched environments") performed against those kept in labs.

She and colleagues modified a robot car kit by adding a clear plastic food container to form a driver compartment with an aluminium plate placed on the bottom.

A copper wire was threaded horizontally across the cab to form three bars: left, centre and right.

When a rat placed itself on the aluminium floor and touched the wire, the circuit was complete and the car moved in the direction selected.

WATCH | Rats trained to drive tiny cars find it relaxing, scientists report

Seventeen rats were trained over several months to drive around an arena made of Plexiglas.

Writing in the journal Behavioural Brain Research, the researchers said the animals could indeed be taught to drive forward as well as steer in more complex navigational patterns.

As she had suspected, Lambert found that the animals kept in stimuli-rich environments performed far better than their lab rat counterparts, but "it was actually quite shocking to me that they were so much better," she said.

The rats' faeces was collected after their trials to test for the stress hormone corticosterone as well as dehydroepiandrosterone, which counters stress.

Rats who drove themselves were less stressed than those who were merely passengers — something that will be familiar to nervous backseat drivers

All rats that underwent training had higher levels dehydroepiandrosterone, indicating a more relaxed state, which could be linked to the satisfaction of gaining mastery over a new skill, referred to as "self-efficacy" or "agency" in humans.

What's more, rats that drove themselves showed higher levels of dehydroepiandrosterone as compared to those who were merely passengers when a human controlled the vehicle, meaning they were less stressed — something that will be familiar to nervous back seat drivers.

The biggest takeaway for Lambert was the potential for new avenues of treatment the work opened up for people suffering from mental health conditions.

"There's no cure for schizophrenia or depression," she said. "And we need to catch up, and I think we need to look at different animal models and different types of tasks and really respect that behaviour can change our neurochemistry."


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