Not taking the criticism lying down, Florence hit back at the Twitter user, who goes by Jesse R.
"I’m told this is a ‘hobo look’. And ga ke ithate [And that I don't love myself]," she tweeted.
An angered Florence went on to lash out at the user.
"Next time I’ll drag people to Venda and back. Le a ntlwaela [You are disrespecting me].”
Subsequently, this spawned a social media stir among users and fans of the actress, who started sharing images of their natural hair, in an effort to denounce attacks against men and women who don't use commercial hair products or put on wigs and weaves.
"What offended me further was her carrying on to say I must love myself. So to her a comb = self-love?" Florence continued, before the hashtag #HoboKeMmao [Hobo is your mother] made it's way on to the Twitter trends list.
"Pat your weave and nurse your fried scalp. Just stay out of my hair. Thanks," Florence added.