"The ambulance driver tried to avoid colliding with the taxi, but he struck four pedestrians on the side of the road. One pedestrian, believed to be 28 years old, died at the scene while three were taken to hospital.
"Two of the pedestrians later passed away. The circumstances surrounding the accident are being investigated," Mbele said.
Meanwhile, Garrith Jamieson of Rescue Care extended their condolences to family and friends of the deceased.
"We will be working closely with the police and helping wherever possible in their investigations," he said.